hyaluronic acid

noun

hy·​al·​uron·​ic acid ˌhī(-ə)l-yu̇-ˈrä-nik How to pronounce hyaluronic acid (audio)
: a viscous glycosaminoglycan chiefly of the matrix of tissues that occurs especially in the vitreous humor, umbilical cord, synovial fluid, and loose connective tissue and serves especially as a structural element and lubricant

Examples of hyaluronic acid in a Sentence

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During winter, Chang also suggests switching to richer creams instead of lotions or gels and layering humectants like glycerin or hyaluronic acid with occlusives to help seal moisture in. Avery Newmark, AJC.com, 5 Feb. 2026 The sport does not prohibit hyaluronic acid, a natural substance that can be used to treat ailments such as osteoarthritis and dry eye, or as a cosmetic filler. Peter Sblendorio, Mercury News, 5 Feb. 2026 Hydrators like hyaluronic acid and glycerin can temporarily plump skin, making crepey texture look smoother. Christa Joanna Lee, Allure, 5 Feb. 2026 Over-the-counter vaginal moisturizers, including products with hyaluronic acid, and water- or silicone-based lubricants, are other options—however, these items won’t address the root of dryness, which is declining estrogen. Erica Sweeney, SELF, 4 Feb. 2026 See All Example Sentences for hyaluronic acid

Word History

Etymology

International Scientific Vocabulary

First Known Use

1934, in the meaning defined above

Time Traveler
The first known use of hyaluronic acid was in 1934

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Cite this Entry

“Hyaluronic acid.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/hyaluronic%20acid. Accessed 16 Feb. 2026.

Medical Definition

hyaluronic acid

noun
hy·​al·​uron·​ic acid ˌhīl-yu̇-ˌrän-ik- How to pronounce hyaluronic acid (audio) ˌhī-əl-yu̇- How to pronounce hyaluronic acid (audio)
: a viscous glycosaminoglycan that occurs especially in the vitreous body, the umbilical cord, and synovial fluid and as a cementing substance in the subcutaneous tissue

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